There's a lot of stuff that's out
there trying to kill us immediately.
And today I'm gonna discuss those that are the most effective at it the deadliest infectious diseases within the world.
How do yourself a favor put away any food?
You might have nearby you and if you
have got a dog, you would
possibly want to maneuver
it into another room.
You might be tempted to mention
that the monstrous bastards.
I'm near to speak about straight away are the deadliest organisms within the world, but that wouldn't really be true because all the
diseases you're gonna hear about today are caused by viruses.
And as you recognize viruses are
just protein covered scum bags filled
with nucleic acids.
So they don't seem to be
generally considered living things.
So still you gotta hand it to him viruses have probably been around for a minimum of tens of immeasurable years and i have managed to form a good living by ripping off our DNA like they're the frickin
Pirate Bay and using it to repeat
themselves and just about master
our asses for as long as they're if in warts but I'm not talking about Ward's
here guys.
It's much worse than that.
I'm talking about the diseases with the
very best known case fatality rates, which is how experts measure the
deadliness of a disease the proportion
of individuals diagnosed with it
who find yourself dying from it
through the Spanish flu 1917 to 1918 killed like 30 million people worldwide
and basically changed the course of
recent history.
That was a strain of an epidemic
called h1n1 and it had a case deathrate
of like 10 to twenty percent
viruses.
I'm talking about are such a lot
deadlier by comparison that Spanish flu is
largely not even worth calling in sick for see instance.
Nipa, which has a median case morbidity of about 50% It's named for
a town in Malaysia where it absolutely
was discovered in 1999 among pig farmers seems a bunch of them started
coming down with severe respiratory problems and inflammation of the brain that
caused hallucinations and seizures and not the nice kinds wait.
There's good types of seizures
outbreak soon followed in India and Bangladesh now along people that
had eaten fruit that was tainted by bats that carried the virus the death rate
in a number of these outbreaks
was 100% and there aren't any
treatments or vaccines for the virus, but what's really pants pooping ly
terrifying about NEPA.
There was a pandemic within the town of Sela Gauri in India
and 75% of these cases were
traced back to folks that had
visited the local hospital just by being in this building they got it.
But hey, that does not affect
you right because odds are you are not
a pig farmer and you're also probably not watching from your place Siliguri.
Well, little question you've heard
of h5n1 the virus formerly referred to
as bird flu has been making the rounds mainly in Asia in Europe where
it's often fatal to birds.
It's rarely contracted by people and it
is not excellent at
jumping from person to person til now
you will remember a long time back once I told you about how scientists
genetically engineered bird flu to
create it contagious among ferrets and that is important because ferrets essentially have the identical system as humans.
Don't request from me why it's assumed
that these new strains are contagious to us also.
Which kind of sucks because the globe
Health Organization says that h5n1 kills a minimum of 54 percent of the folks that comprehend
usually from respiratory problems.
Now, there's a vaccine for the
strain that's go in the globe immediately, but a minimum
of within the u.s.
It's been stockpiled by the govt.
Yes, as for the strains that were made to be contagious between mammals.
They're currently kept under lock and key in labs in Wisconsin and therefore the Netherlands
hopefully big lock with thumbprint and retinal scanner voice activated and a few of the scientists who
monkeyed with the virus have said that they've developed a vaccine a minimum of for the strains that they
invented.
So that's great.
They can release it on the planet
then sell the vaccine.
That'll be great business for them.
Now Hank, you're saying I'm not a Malaysian bat handler and i have already stocked my pantry with enough skittles and Diet
Sierra Mist and find me through
the bird flu pandemic come as if i do
not know.
All right.
Starts with German scientists and lab monkeys, although scientists started
coming down with some gut-wrenchingly flopsweat inducing lee horrible symptoms
wicked fevers diarrhea vomiting massive internal bleeding until for several of them their circulatory.
Timms just stop working.
It didn't take long for the scientists to
work out that there was a correlation between messin with monkey parts
and contracting the disease.
So they basically started studying themselves and their sickness and isolated
the virus.
That is today called Marburg haemorrhagic fever the primary outbreak in 1967 killed
23% of the scientists and in some countries including the u. s., that's still the official case deathrate.
The thing is Marburg keeps exposure
mainly in Central Africa and
when it does it kills over 80
percent of its victims and outbreaks affecting many people unlike NEPA though, which are everywhere the place when they're actually infected with them.
It's not something you generally consider
it's like how would i buy that
person's poop on me?
Oh because his butt is exploding and
that we should all be thanking our gods for that because otherwise it'd be lights out.
The World Health Organisation says that Marburg is one in all the foremost
virulent pathogens to ever infect humans and national security types put
Marburg on the highest of the
list of viruses that you just don't want crazy people getting their
hands on and when those German scientists first isolated the Marburg virus, they realized that they
were handling an entire new class of scumbag a pestilence that contains a completely different shape
and attacked the human vascular system.
What that they had discovered
was the virus family filoviridae this unwholesome lot includes a cousin of
Marburg.
That is the second most fatal disease on our list zaire ebolavirus or z bhav as
you'll be able to tell from its
name z Bob is simply one among five species of the filovirus and it is the one that's accountable
for the foremost
outbreaks and is out and away
the deadliest like Marburg Z both causes a good range of flu-like symptoms.
Like I'm gonna do the smiling vomiting and fever then moves on to failure of blood vessels causing bleeding under
the skin from mucous.
Membranes.
Is it better when I'm smiling but unlike Marburg C buff has a mean mortality rate of 83% in outbreaks within the republic of congo within the early 2000s, it killed quite 90% of the people and infected.
So, how could you most likely get any worse than that?
What disease is deadlier than 90% fatal?
And in reproval sick and corner of the globe?
Does it thrive what I'm visiting tell you and it should be a bit bit surprising but first you may want to place your dog in another room the deadliest disease within the world the one with the very best nearly always worst case scenario nearly perfect batting average deathrate rabies.
I know you are like, huh, you mean my adorable retriever up here may be a vector for the best plague known to humanity isn't rabies like everywhere and is not there a vaccine indeed all as true?
But the very fact is that rabies includes a case mortality of a few hundred percent.
Once you have been diagnosed with symptoms of the disease, it means almost certain death.
There are fewer than 10 recorded cases of individuals exhibiting symptoms of rabies then living to inform about it but 10.
So why hasn't the rabies virus brought humanity to its knees three reasons one unlike all the opposite filthy scumbags I've talked about today.
There's a vaccine that's widely available for the rabies virus Pasteur developed it within the 1880s using tissue of dead infected rabbits.
And since then the ball's just about been in our court, but it is important to recollect a vaccine isn't a cure.
It's just a preventative which brings us to reason to rabies encompasses a really long time period that is the time between when you're infected and when your symptoms start to look Marburg and Ebola have incubation periods of just some days, except for rabies, it's like two to 3 months which means you've got almost 12 weeks to urge vaccinated for rabies even after you have been infected and therefore the vaccine will prevent the onset of symptoms.
So you're basically taking the preventative treatment even after the viruses in your body, but you are not quite infected yet.
And the third reason we're beating rabies is education a minimum of in developed countries public health education has been so good for thus long that folks get vaccinated as soon as they're bitten by an animal and in many places vaccinating pets is required by law.
It's a sterling public health victory, but rabies remains a heavy problem in developing countries where both public health education and access to health care are scarce and it's a terrible thanks to go early symptoms are flu-like, but after a pair of days the virus targets the central system, and so the victims become agitated and delirious and sometimes begin to experience seizures paralysis strikes.
Mostly the throat within the jaw making it difficult to swallow which is why patients avoid water giving it the nickname hydrophobia.
So the pulse and vital sign begin to vary wildly often resulting in coma and eventually cardiopathy.
So there's that NEPA h5n1 Marburg zebra of rabies, but what do these executable conditions have in common?
Well, one thing you'll have noticed is that every one of those diseases are zoonotic meaning that they are transmitted to humans from animals or originally were anyway with the exception of bird flu.
Especially, i do not comprehend you, but my plans of adopting a pet bat are totally off the table now and what makes them transmissible.
Well of these viruses belong to the current order of viruses.
You can attempt to pronounce it.
I'm not visiting but they're bullet shaped viruses with one strand of RNA inside.
They're excellent at connecting with animal and plant cells and since they lack the enzyme that proofreads its RNA after it's copied.
It mutates really easily and really quickly for these and other reasons.